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About
research
Research is not the pursuit of answers alone — it is a disciplined act of curiosity, inquiry, and responsibility, advancing knowledge in service of health, humanity, and the greater good.
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Ongoing Research
We are a research-based university and as such, we are proud to be actively involved in ongoing global research projects. These are intended to produce valuable data and outcomes that will be used to improve the health and welfare of people around the world. Some of our notable ongoing research studies include:
Herbozone™
Herbozone™ Research Institute
Oxygen therapies, including ozone therapy, have been used in research and therapy globally for over 100 years. The combination of these therapies with plant-based adjuncts have a demonstrated success record in the world of healing. We actively research different methodologies using various combinations. The Herbozone™ Research Institute is engaged in research in this arena. We study the effectiveness of our unique combination of oxygen therapy with specialized, naturally-occurring salts to optimize the eradication of microbial vectors across a variety of ailments, and also the effectiveness of these in the elimination of root causes of health challenges.
This technique has been developed by and is currently used by Dr. Bill Akpinar. It has demonstrated a high degree of effectiveness in addressing many health challenges.
Acustem™
The Acustem Research Institute includes investigation and research into methodologies involving the union of Chinese Medicine and cell therapies.
Applications are used to address and potentially show benefit in resolving global health imbalances, which are currently undergoing investigational research.
Native American and Indigenous Nations Spiritual Health and Welfare research institute
As part of our Native American Nations Joint Property Treaty Trust Research Institute, UHSS is involved in ongoing research related to spiritual-based healing practices used for millennia throughout the world.
Among our noted principal founders are members and medicine men of Native American (a.k.a. American Indian) tribes. In this institute of our university, we place a high degree of emphasis on researching, investigating and working with various spiritually-based methodologies, protocols and healing ceremonies used in Native American and other indigenous cultures.
Our goal is to help keep these alive for future generations in order to guarantee their perpetuity. Because of our dedication and mission to help indigenous peoples around the world, we offer full study scholarships to members of Native American and other indigenous tribes who have a sincere desire and dedication to become part of our university. There are many beneficial components of indigenous spiritual traditions that can benefit the rest of humanity.
ProloVive™
ProloVive™
Research Institute
Cell therapies offer great promise to help address modern-day health afflictions. Cell therapies, in their many different forms and applications, are currently under investigation in this part of our university.
Light Genomics™
Light Genomics Research Institute
There are endless references to light in scripture as well as knowledge passed down by sages in history, and rightfully so. Light is referenced in spiritual belief and practice systems and is an incredible tool to help address health afflictions.
Currently, we are investigating different applications of light to the healing model.
Regenerative Medicine
Regenerative Medicine Research Institute
Research related to the emerging and exciting field of Regenerative Medicine is currently being undertaken. A powerful component of spirituality is inherent in Regenerative Medicine and studies in this area will be of benefit to address the many health challenges humanity faces today.
Spiritual Scientific Care/Counseling™
Spiritual Scientific Care/Counseling Research™ Institute
Spiritual Scientific Care/Counseling Research™ is a proprietary method whereby the foundations presented to us through various scriptures, traditions of the world and through the writings of sages and holy men and women are systematically studied so they may be made available for use by the global community of humanity. Our purpose is to assess and disseminate these truths. Use of all modern tools of technology will be used in this specialized form of beneficial research.
Stem cell research is not merely the study of cells — it is the exploration of regeneration, possibility, and the science of renewal in pursuit of healing and human advancement.
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the stem cell research
The University of Health and Spiritual Sciences™ In conjunction with the University of Integrative Medicine™ proudly presents therapeutic clinical FDA and Institutional Review Board approved protocols under which practitioners can utilize one of the greatest developments in Regenerative and Restorative Medicine. This is the use of stem cells as a part of your approved therapeutic clinical research protocols.
The FDA oversees tissue transplant products, including stem cells, and enforces rigorous industry standards to ensure patient safety. When cellular and tissue products meet the FDA’s established criteria, they are designated as HCT/P 361 products rather than being classified as drugs. Although these products are subject to FDA regulation, they do not undergo the full FDA approval process. This makes it crucial to select companies with a transparent and well-documented history of FDA interactions when procuring these products.
Recognizing the potential of stem cell therapies to treat a variety of medical conditions, the FDA has implemented stringent regulatory measures. Manufacturers are regularly reviewed to ensure compliance with established protocols. During these inspections, investigators are required to provide detailed insights into their manufacturing processes, allowing the FDA to confirm that all necessary steps are being taken to ensure the product’s safety, purity, and efficacy.
While the exact mechanisms behind cellular therapies—renowned for their potential to deliver lasting healing—remain not entirely understood, a wealth of anecdotal evidence and numerous case studies are gradually shedding light on this intricate and promising field. Because biologic grafts, cellular therapies, and tissue products consist of a vast array of molecules and complex structures, fully deciphering how well-executed regenerative treatments work will require time and continued research.
Always prioritizing safety, the UHSS™ special clinical IRB research protocol will keep driving forward our understanding of these mechanisms and best practices in regenerative and restorative medicine. In the meantime, buoyed by our exceptional safety record, we are excited to see these therapies continue to benefit physicians committed to advancing care for their research participants. The UHSS™ research directors as part of our Acu Stem Technique™ and protocols will remain diligent in collecting and analyzing data to further unlock and maximize the potential of regenerative and restorative medicine. The benefit to the clinical researcher who is involved with The UHSS™ therapeutic clinical research methodologies is that all your data is privileged, confidential and protected by law, giving you a distinct advantage and privacy over other research methodologies available.
Mesenchymal Stem Cells (MSCs) are self-renewing, multipotent progenitor cells capable of differentiating into various cell types and tissues. Research shows that MSCs are present in numerous tissues throughout life; however, their numbers and functional characteristics tend to decline with age, with older MSCs often behaving differently than those from younger sources. Despite these changes, MSCs remain highly promising, whether sourced from an individual’s own aging cells or from postnatal tissues.
Moreover, MSCs exhibit significant indirect local effects—comparable to paracrine activity—that can persist for several weeks or more. They appear to adapt to their surrounding environment, acting much like revitalized defenders that can stimulate targeted regeneration when the host cells have lost their full capacity to do so.
Notably, postnatal tissues boast high concentrations of MSCs across various compartments. These cells are characterized by a more robust secretome, quicker cell division, and a lower propensity for teratoma formation, underscoring their enhanced therapeutic potential.
Totipotent Stem Cells
Totipotent cells—often referred to as embryonic stem cells—possess the extraordinary ability to develop into any cell type or tissue, including extraembryonic structures like placental cells. While this remarkable potential suggests vast opportunities, the significant risk of teratoma formation renders these cells unsuitable for therapeutic applications, and their use is prohibited in the United States.
Pluripotent Stem Cells
Pluripotent stem cells can transform into any cell type in the body, giving rise to tissues derived from all three embryonic germ layers: endoderm, mesoderm, and ectoderm.
Multipotent Stem Cells
Multipotent stem cells, while capable of generating various cell types, have a more limited differentiation potential compared to pluripotent cells. They can be found in postnatal tissues such as the umbilical cord and placenta, as well as in adult tissues, serving as a vital reservoir for growth and repair. Each type of multipotent stem cell differentiates into a specific subset of cells. Although isolating these cells for clinical applications can be challenging, they are considered ethically sound. Examples include hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs).
MSC's in Postnatal Tissues
MSC’s were first identified in the adherent fraction of bone marrow stroma. They were termed CFU-Fs because of their ability to generate single cell-derived colonies, in analogy to their hematopoietic counterparts, CFU-Fs from almost all embryonic and postnatal tissues can be expanded in vitro to generate cell cultures that conserve trilineage potential. The role of MSC’s in multiple anatomical locations, and whether they constitute a specific homogeneous cell type or a mixed population of tissue-specific cells heterogenous in nature and origin, is not well understood. However, these progenitors express pericyte-specific cell-surfaced markers such as NG2 and PDGRRB and are located in perivascular regions of the different tissues in which they reside.
MSC Expansion in Vitro
Mesenchymal stem cells (MSCs) can be expanded in vitro by culturing them as adherent cells in two-dimensional monolayers using specialized media. Our specialized research based methodologies utilize the best of technology to provide cells which are superior is quality and quantity. These expanded cells, often referred to as multipotent mesenchymal stromal cells, are characterized by the expression of markers CD73, CD90, and DC105, while lacking CD11b, CD19, CD34, CD45, and HLADR. In this context, we refer to the in vitro-expanded cells simply as mesenchymal stromal cells.
MSC Differentiation Potential
The primary characteristic of multipotent mesenchymal stromal cells is their ability to differentiate into mature adipocytes, chondrocytes, and osteoblasts under specific culture conditions. Our cells which have been specifically harvested, cultured and selected for our research protocols exhibit unique cell signaling and paracrine properties. Their level of safety and efficacy are clearly above industry standards. They have specifically designated for therapeutic clinical research under strict Institutional review board scrutiny and analyses.
The UHSS™ Acu Stem Technique™ protocol incorporates a rigorous quality program aimed at preventing, identifying, and rectifying any deficiencies that could elevate the risk of introducing, transmitting, or spreading communicable diseases. This quality program covers all products, services, and researchers at The UHSS™, as well as relevant contracted service providers.
These are cells having been prepared using proprietary technology and possessing unique characteristics which have been designated to be used for therapeutic clinical research under approved IRB’s in conjunction with the University of Health and Spiritual Sciences™ and University of Integrative Medicine™ clinical Institutional Review Board consortium.
Additionally, our product processing entities adhere to the FDA’s minimal manipulation requirements, ensuring that the products remain free of contaminants or harmful components, while preserving the essential biological characteristics of the cells and tissues.